Allogenic leukocyte immunization after five or more miscarriages. Recurrent Miscarriage Immunotherapy Trialists Group
نویسندگان
چکیده
منابع مشابه
Allogenic leukocyte immunization after five or more miscarriages. Recurrent Miscarriage Immunotherapy Trialists Group.
Rather than investigate whether paternal leukocyte immunization improves the live birth rate in women with three or more abortions, we analysed the results of patients expected to have a poor outcome in a subsequent pregnancy if untreated, i.e. women with five or more abortions and no anti-paternal complement-dependent antibody (APCA) at initial testing. The analysis included the results of pat...
متن کاملEffectiveness of Leukocyte Immunotherapy in Primary Recurrent Spontaneous Abortion (RSA)
Background: Recurrent spontaneous abortion (RSA) is defined as three or more se-quential abortions before the twentieth week of gestation. There are evidences to sup-port an allo-immunologic mechanism for RSA. One of the methods for treatment of RSA is leukocyte therapy; however there is still controversy about effectiveness of this method. Objectives: To evaluate the effectiveness of leukocyte...
متن کاملComplement as a predictor of further miscarriage in couples with recurrent miscarriages.
BACKGROUND The clinical significance of complement is unclear in patients with unexplained recurrent miscarriage, though low levels of complement 3 (C3) and/or complement 4 (C4) are reported to be associated with the antiphospholipid syndrome (aPS). We therefore investigated whether C3 and C4 have a predictive value for subsequent miscarriages. METHODS In total, 215 patients with a history of...
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BACKGROUND Reproductive loss carries immeasurable human costs as well as being costly to the health care system. The objectives of this study were to determine the frequency and distribution of cytogenetically abnormal miscarriages from couples with recurrent miscarriage and to compare the results with the general population. METHODS A total of 420 specimens, including 29 pre-clinical, 237 em...
متن کاملeffectiveness of leukocyte immunotherapy in primary recurrent spontaneous abortion (rsa)
background: recurrent spontaneous abortion (rsa) is defined as three or more se-quential abortions before the twentieth week of gestation. there are evidences to sup-port an allo-immunologic mechanism for rsa. one of the methods for treatment of rsa is leukocyte therapy; however there is still controversy about effectiveness of this method. objectives: to evaluate the effectiveness of leukocyte...
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ژورنال
عنوان ژورنال: Human Reproduction
سال: 1997
ISSN: 0268-1161,1460-2350
DOI: 10.1093/humrep/12.2.250